关闭
 
读者在线:用户名 密码
首页 期刊简介 投稿须知 期刊目录 专家风采 编委会 特邀顾问 联系我们 移动出版
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5



刊物信息

期刊名称:药物分析杂志
主管单位:中国科学技术协会
主办单位:中国药学会
承办:中国食品药品检定研究院
主编:金少鸿
地址:北京天坛西里2号
邮政编码:100050
电话:010-67012819,67058427
电子邮箱:ywfx@nicpbp.org.cn
国际标准刊号:ISSN 0254-1793
国内统一刊号:CN 11-2224/R
邮发代号:2-237
 

访问统计
您是第  4 9 9 2 2 5 6 位浏览者
您当前的位置:首页 >> 正文

中药材及饮片中重金属及有害元素限量制定的探讨

Exploration of the limit of heavy metals and harmful elements in Chinese medicinal materials and decoction pieces

分类号:R917
出版年·卷·期(页码):2020,40 (4):688-693
DOI: 10.16155/j.0254-1793.2017.01.01
-----摘要:-------------------------------------------------------------------------------------------

中药材及饮片中重金属及有害元素最大限量理论值是制定科学、合理的限量标准的重要基础。本文重点针对《中华人民共和国药典》(简称《中国药典》)2015年版四部"中药有害残留物限量制定指导原则"中重金属及有害元素最大限量理论值计算公式的修订背景和修订内容,限量制定的一般步骤以及植物类中药材中重金属及有害元素一致性限量标准的制定过程进行探讨。同时,将《中国药典》标准与ISO限量制定的异同进行比较论述。制定适用于中国国情的、符合中药使用特点的中药材及饮片中重金属及有害元素最大限量理论值的计算公式,并推行科学、合理的残留限量标准,为保障人民用药安全,并促进中药产业的可持续、健康发展具有重要的实际意义。

-----英文摘要:---------------------------------------------------------------------------------------

The theoretical value of the maximum limit of heavy metals and harmful elements in Chinese medicinal materials and decoction pieces is an important basis for the establishment of scientific and reasonable limit standards.This paper focused on the background and the revision of the theoretical value of the maximum limit of heavy metals and harmful elements in "Guideline for the Formulation of the Limit of Harmful Residue of Traditional Chinese Medicine(TCM)" in Pharmacopoeia of the People's Republic of China(Chinese Pharmacopoeia),2015 edition,Volume Ⅳ.And the similarities and differences between standards in Chinese Pharmacopoeia and ISO limit were compared.It is of crucial practical significance to formulate the theoretical maximum limit formula of heavy metals and harmful elements in Chinese medicinal materials and decoction pieces that are suitable for the national conditions and applicable to traditional Chinese medicines in order to formulate the scientific and reasonable residue limit standards,considering the drug safety insurance and the sustainable and healthy development of the TCM industry.

-----参考文献:---------------------------------------------------------------------------------------
[1] 刘丽娜,李耀磊,金红宇,等.免疫亲和净化HPLC柱后光化学衍生荧光法测定动物药中黄曲霉毒素[J].中草药,2017,48(6):1220 LIU LN,LI YL,JIN HY,et al.Determination of aflatoxins in animal medicines by immunoaffinity column and HPLC-FLD with photochemical derivatization fluorescence detection[J].Chin Tradit Herb Drugs,2017,48(6):1220
[2] 孙艳,赵余庆.药食同源品中重金属的检测方法与思考[J].中草药,2011,42(11):2351 SUN Y,ZHAO YQ.Consideration and detection methods of heavy metals in medicinal and edible goods[J].Chin Tradit Herb Drugs,2011,42(11):2351
[3] BJ?RNBERG KA,VAHTER M,PERTERSSON-GRAWé K,et al.Methyl mercury and inorganic mercury in Swedish pregnant women and in cord blood:influence of fish consumption[J].Environ Health Perspect,2003,111(4):637
[4] CHEN X,WANG K,WANG Z,et al.Effects of lead and cadmium co-exposure on bone mineral density in a Chinese population[J].Bone,2014,63(6):76
[5] CHEN CY,DRISCOLL CT.Integrating mercury research and policy in a changing world[J].Ambio,2018,47(2):111
[6] KASHYAP R,VERMA KS,UNIYAL SK,et al.Geospatial distribution of metal(loid)s and human health risk assessment due to intake of contaminated groundwater around an industrial hub of northern India[J].Environ Monit Assess,2018,190(3):136
[7] MAGHAKYAN N,TEPANOSYAN G,BELYAEVA O,et al.Assessment of pollution levels and human health risk of heavy metals in dust deposited on Yerevan's tree leaves(Armenia)[J].Acta Geochim,2017,36(1):16
[8] 中华人民共和国药典2015年版.四部[S].2015:402 ChP 2015.Vol Ⅳ[S].2015:402
[9] 左甜甜,王莹,张磊,等.中药中外源性有害残留物安全风险评估技术指导原则[J].药物分析杂志,2019,39(10):1399 ZUO TT,WANG Y,ZHANG L,et al.Guideline of risk assessment of exogenous harmful residues in traditional Chinese medicines[J].Chin J Pharm Anal,2019,39(10):1399
[10] Summary Report of the Seventy-Third Meeting of JECFA[EB/OL].Geneva:Joint FAO/WHO Expert Committee on Food Additives.(2010-06-24)[2012-06-09]:http://www.who.int/foodsafety/publications/jecfa-reports/en/
[11] Summary Report of the Seventy-Second Meeting of JECFA[EB/OL].Rome:Joint FAO/WHO Expert Committee on Food Additives.(2010-02-16)[2012-06-04].http://www.who.int/foodsafety/publications/chem/summary72.pdfua=1
[12] 王彝白纳,刘爱东,李建文,等.11省市成年居民中药消费状况调查[J].中国药事,2017,31(6):666 WANG YBN,LIU AD,LI JW,et al.The survey of traditional chinese medicine consumption among adult residents in 11 provinces and cities[J].Chin Pharm Aff,2017,31(6):666
[13] 潘兰,贾新岳,石明辉,等.6种药材中5种重金属转移率的测定[J].中成药,2017,39(6):1315 PAN L,JIA XY,SHI MH,et al.Determination of the transfer rates of 5 heavy metals in 6 traditional Chinese medicinal materials[J].Chin Tradit Pat Med,2017,39(6):1315
[14] 甘彦雄,郑勇凤,汪蕾,等.基于ICP-MS分析蓬莪术醋制前后煎液及沉淀物重金属转移率变化[J].中国中药杂志,2016,41(1):65 GAN YX,ZHENG YF,WANG L,et al.Analysis on transfer rate change of heavy metal in decoction and precipitation of Curcuma phaeocaulis before and after processing with vinegar based on ICP-MS[J].China J Chin Mater Med,2016,41(1):65
[15] 金力薇,赵灵佳,岳显可,等.十全大补膏及其组方药材重金属残留分析[J].实用药物与临床,2017,20(11):1310 JIN LW,ZHAO LJ,YUE XK,et al.Determination of heavy metal residues in Shiquan Dabu herb paste and its Chinese herbal pieces[J].Pract Pharm Clin Rem,2017,20(11):1310
[16] 王国海,郭耀武,乔蓉霞,等.药材煎煮前后重金属及有害元素转移率的研究[J].安徽医药,2014,18(11):2072 WANG GH,GUO YW,QIAO RX,et al.Study on the transfer rate of heavy metals and harmful elements in traditional Chinese medicinal materials before and after decoction[J].Anhui Med Pharm J,2014,18(11):2072
[17] 左甜甜,张磊,金红宇,等.中药材提取前后重金属及有害元素转移率和分级别风险评估的研究[J].药物分析杂志,2017,37(8):1398. ZUO TT,ZHANG L,JIN HY,et al.Research of transfer rates of heavy metals and harmful elements in tradition Chinese medicines before and after extraction and tiered risk assessment[J].Chin J Pharm Anal,2017,37(8):1398
[18] GB 2762-2017食品中污染物限量.食品安全国家标准[S].2017:1 GB 2762-2017 Limits of Pollutants in Food.National Standard for Food Safety[S].2017:1
[19] ISO 18664 Traditional Chinese Medicine-Determination of Heavy Metals in Herbal Medicines used in Traditional Chinese Medicine[S].2015:7

欢迎阅读《药物分析杂志》!您是该文第 90位读者!

药物分析杂志 © 2009
地址:北京天坛西里2号 邮政编码:100050; 电子邮件:ywfx@nicpbp.org.cn

本系统由北京博思汇文数字科技有限公司设计开发 技术服务电话:400-921-9838